diff --git a/src/OpenColorIO/CMakeLists.txt b/src/OpenColorIO/CMakeLists.txt
index 646423e97..770d706f2 100755
--- a/src/OpenColorIO/CMakeLists.txt
+++ b/src/OpenColorIO/CMakeLists.txt
@@ -336,7 +336,7 @@ if(OCIO_USE_SIMD AND OCIO_USE_SSE2NEON AND COMPILER_SUPPORTS_SSE_WITH_SSE2NEON)
     target_link_libraries(OpenColorIO PRIVATE $<BUILD_INTERFACE:sse2neon>)
 endif()
 
-if(APPLE)
+if(CMAKE_SYSTEM_NAME STREQUAL "Darwin")
     target_link_libraries(OpenColorIO
         PRIVATE
             "-framework ColorSync"
diff --git a/src/OpenColorIO/SystemMonitor.cpp b/src/OpenColorIO/SystemMonitor.cpp
index 7fcc9c366..3ce037873 100644
--- a/src/OpenColorIO/SystemMonitor.cpp
+++ b/src/OpenColorIO/SystemMonitor.cpp
@@ -6,6 +6,10 @@
 #include <string>
 #include <string.h>
 
+#if defined(__APPLE__)
+#include <TargetConditionals.h>
+#endif
+
 #include <OpenColorIO/OpenColorIO.h>
 
 #include "Logging.h"
@@ -26,7 +30,7 @@ void SystemMonitorsImpl::getAllMonitors()
 
 } // namespace OCIO_NAMESPACE
 
-#elif __APPLE__
+#elif defined(__APPLE__) && TARGET_OS_OSX
 
 #include "SystemMonitor_macos.cpp"
 
diff --git a/tests/cpu/CMakeLists.txt b/tests/cpu/CMakeLists.txt
index 55a25588b..c71531ba2 100755
--- a/tests/cpu/CMakeLists.txt
+++ b/tests/cpu/CMakeLists.txt
@@ -63,7 +63,7 @@ function(add_ocio_test NAME SOURCES TESTS PRIVATE_INCLUDES)
         target_link_libraries(${TEST_BINARY} PRIVATE sse2neon)
     endif()
 
-    if(APPLE)
+    if(CMAKE_SYSTEM_NAME STREQUAL "Darwin")
         # Frameworks needed to access the ICC monitor profile.
         target_link_libraries(${TEST_BINARY}
             PRIVATE
@@ -72,7 +72,7 @@ function(add_ocio_test NAME SOURCES TESTS PRIVATE_INCLUDES)
                 "-framework CoreGraphics"
                 "-framework IOKit"
         )
-    endif(APPLE)
+    endif()
 
     if(PRIVATE_INCLUDES)
         target_include_directories(${TEST_BINARY}
diff --git a/tests/cpu/Config_tests.cpp b/tests/cpu/Config_tests.cpp
index ed72a5e17..0ffbb42d3 100644
--- a/tests/cpu/Config_tests.cpp
+++ b/tests/cpu/Config_tests.cpp
@@ -4,6 +4,10 @@
 
 #include <sys/stat.h>
 
+#if defined(__APPLE__)
+#include <TargetConditionals.h>
+#endif
+
 #include <pystring.h>
 
 #include "Config.cpp"
@@ -9845,7 +9849,8 @@ active_views: []
         = std::string(OCIO::GetTestFilesDir()) + "/icc-test-1.icc";
 
 
-#if !defined(OCIO_HEADLESS_ENABLED) && ( defined(__APPLE__) || defined(_WIN32) )
+#if !defined(OCIO_HEADLESS_ENABLED) && \
+    ( defined(_WIN32) || ( defined(__APPLE__) && TARGET_OS_OSX ) )
 
     OCIO_CHECK_ASSERT(OCIO::SystemMonitors::Get()->isSupported());
 
@@ -10070,7 +10075,8 @@ active_views: [view]
     // Only the 'view' view is active.
     OCIO_CHECK_EQUAL(1, config->getNumViews("sRGB"));
 
-#if !defined(OCIO_HEADLESS_ENABLED) && ( defined(__APPLE__) || defined(_WIN32) )
+#if !defined(OCIO_HEADLESS_ENABLED) && \
+    ( defined(_WIN32) || ( defined(__APPLE__) && TARGET_OS_OSX ) )
 
     OCIO_CHECK_ASSERT(OCIO::SystemMonitors::Get()->isSupported());